Publications

Publications

For a comprehensive list of my publications, please see ORCID iD: https://orcid.org/0000-0002-7372-0725

JOURNALS

Dubash S, Barwick TD, Kozlowski K, Rockall AG, Khan S, Khan S, Yusuf S, Lamarca A, Valle JW, Hubner RA, McNamara MG, Frilling A, Tan T, Wernig F, Todd J, Meeran K, Pratap B, Azeem S, Huiban M, Keat N, Lozano-Kuehne JP, Aboagye EO, Sharma R (2024). Somatostatin Receptor Imaging with [18F]FET-βAG-TOCA PET/CT and [68Ga]Ga-DOTA-Peptide PET/CT in Patients with Neuroendocrine Tumors: A Prospective, Phase 2 Comparative Study. Journal of Nuclear Medicine March 2024, 65 (3) 416-422. (https://doi.org/10.2967/jnumed.123.266601)

Aravind P, Popat S, Barwick TD, Soneji N, Lythgoe M, Sreter KB, Lozano-Kuehne JP, Bergqvist M, Patel N, Aboagye EO, Kenny LM (2023). A subset of non-small cell lung cancer patients treated with Pemetrexed show 18F-Fluorothymidine “Flare” on Positron Emission Tomography. Cancers 2023, 15(14), 3718. (https://doi.org/10.3390/cancers15143718)

Cunnea P, Curry E, Christie E, Nixon K, Kwok CH, Pandey A, Wulandari R, Thol K, Ploski J, Morera-Albert C, McQuaid S, Lozano-Kuehne J, Clark JJ, Krell J, Stronach E, McNeish I, Bowtell D, Fotopoulou C (2023). Spatial and temporal intra-tumoural heterogeneity in advanced High-Grade Serous Ovarian Cancer: implications for surgical and clinical outcomes. Cell Reports Medicine. Volume 4, ISSUE 6, 101055. ISSN:2666-3791. (https://doi.org/10.1016/j.xcrm.2023.101055)

Lythgoe M, Dama P, Frampton AE, Pickford E, Tookman L, Cunnea P, Fotopoulou C, Liu D, Clark J, Lozano-Kuehne J, Badman PD, Clarke A, Chetal S, Fyvie G, Stevenson A, Krell J (2023). Immune modulation and the oral live biotherapeutic product, MRx0518, in treatment-naïve patients with cancer: Updated safety data. Journal of Clinical Oncology 41, no. 16_suppl (June 01, 2023) 3145-3145. (https://ascopubs.org/doi/10.1200/JCO.2023.41.16_suppl.3145)

Coombes RC, Badman PD, Lozano-Kuehne JP, Liu X, Macpherson IR, Zubairi I, Baird RD, Rosenfeld N, Garcia-Corbacho J, Cresti N, Plummer R, Armstrong A, Allerton R, Landers D, Nicholas H, McLellan L, Lim A, Mouliere F, Pardo OE, Ferguson V, Seckl MJ (2022). Results of the Phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer. Nature Communications. (https://www.nature.com/articles/s41467-022-30666-0)

Kenny LM, Gilbert FJ, Gopalakrishnan G, Aravind P, Barwick T, Patel N, Hiscock DR, Boros I, Kealey S, Aigbirhio FI, Lozano-Kuehne J, Cleator SJ, Fleming B, Riddle P, Ahmad R, Chua S, Johnston SRD, Mansi J, Cook GJ, Aboagye EO (2022). The HERPET study: Imaging HER2 expression in breast cancer with the novel PET tracer [18F]GE-226, a first-in-patient study. Journal of Clinical Oncology 2022 40:16_suppl, 3069-3069.

Aravind P, Popat S, Barwick TD, Soneji N, Lythgoe M, Lozano-Kuehne J, Sreter KB, Bergqvist M, Patel NH, Aboagye EO, Kenny LM (2022). [18F]Fluorothymidine(FLT)-PET imaging of thymidine kinase 1 pharmacodynamics in non-small cell lung cancer treated with pemetrexed. Journal of Clinical Oncology 2022 40:16_suppl, 3070-3070.

Braga A, Paiva G, Ghorani E, Freitas F, Velarde LGC, Kaur B, Unsworth N; Lozano-Kuehne J, Esteves APVS, Filho JR, Junior JA, Aguiar X, Sarwar N, Elias KM, Horowitz NS, Berkowitz RS, Seckl MJ (2021). Predictors for single-agent resistance in FIGO score 5 or 6 gestational trophoblastic neoplasia: an international, multicentre, retrospective study,  Lancet Oncology (https://doi.org/10.1016/S1470-2045(21)00262-X)

Pinato DJ, Kaseb A, Wang Y, Saeed A, Szafron D, Jun T, Dharmapuri S, Naqash AR, Muzaffar M, Navaid M, Khan U, Lee C, Bulumulle A, Yu B, Paul S, Fessas P, Nimkar N, Bettinger D, Hildebrand H, Pressiani T, Abugabal YI, Personeni N, Huang Y-H, Lozano-Kuehne J, Rimassa L, Ang C, Marron TU (2020). Impact of corticosteroid therapy on the outcomes of hepatocellular carcinoma treated with immune checkpoint inhibitor therapy, Journal for Immunotherapy of Cancer, Vol:8, Pages:e000726-e000726

Sharma R, Valls PO, Inglese M, Dubash S, Chen M, Gabra H, Montes A, Challapalli A, Arshad M, Tharakan G, Chambers E, Cole T, Lozano-Kuehne JP, Barwick TD, Aboagye EO (2020). [18F]Fluciclatide PET as a biomarker of response to combination therapy of pazopanib and paclitaxel in platinum-resistant/refractory ovarian cancer, European Journal of Nuclear Medicine and Molecular Imaging, ISSN:0340-6997.

Trousil S, Lee P, Edwards RJ, Maslen L, Lozano‐Kuehne JP, Ramaswami R, Aboagye EO, Clarke S, Liddle C, Sharma R. (2019). Altered cytochrome 2E1 and 3A P450‐dependent drug metabolism in advanced ovarian cancer correlates to tumour‐associated inflammation. British Journal of Pharmacology. (https://doi.org/10.1111/bph.14776)

Sharma R, Valls PO, Inglese M, Dubash   SR, Chen M, Gabra H, Montes A, Challapalli A, Tharakan G, Chambers E, Cole T,   Lozano-Kuehne J, Barwick T, Aboagye E. (2019). [18F] Fluciclatide PET as a biomarker of clinical response to combination therapy of pazopanib and paclitaxel in patients with platinum-resistant or platinum-refractory advanced ovarian cancer: Results of a phase Ib study. Journal of Clinical Oncology 37:15_suppl, 3070-3070. (https://ascopubs.org/doi/abs/10.1200/JCO.2019.37.15_suppl.3070)

Mihaylova B, Schlackow I, Herrington W, Lozano-Kühne J, Kent S, Emberson J, Reith C, Haynes R, Cass A, Craig J, Gray A, Collins R, Landray M, Baigent C. (2016). Cost-effectiveness of simvastatin plus ezetimibe for cardiovascular prevention in chronic kidney disease: results of   the SHARP trial. American Journal of Kidney Diseases. Am J Kidney Dis. 2016 Apr; 67(4): 576–584. (http://dx.doi.org/10.1053/j.ajkd.2015.09.020)

Kent S, Schlackow I, Lozano-Kühne J, Reith C, Emberson J, Haynes R, Gray A, Cass A, Baigent C, Landray MJ, Herrington W, Mihaylova B. (2015). What is the impact of chronic kidney disease stage and cardiovascular disease on the annual cost of hospital care in moderate-to-severe kidney disease? BMC Nephrology 16:65 (DOI 10.1186/s12882-015-0054-0).

Gabud RS, Aguila MER, Manalang Jr GF, Chua RB, Mendoza ER, Lozano-Kühne JP (2015). An assessment of chronotype and social jet lag among Filipinos. International Journal of Philippine Science and Technology 1(1):31-40. 

Baclig MO, Lozano-Kühne JP, Mapua CA, Gopez-Cervantes J, Natividad FF, (2014). Genetic Variation I148M in Patatin-Like Phospholipase 3 Gene and Risk of Non-Alcoholic Fatty Liver Disease Among Filipinos. Int J Clin Exp Med 2014;7(8):2129-2136 www.ijcem.com /ISSN:1940-5901/IJCEM0001123.

Baclig MO, Alvarez MR, Lozada XMR, Mapua CA, Lozano-Kühne JP, Dimamay MPS, Natividad FF, Gopez-Cervantes J, Matias RR (2012). Association of glutathione S-transferase T1 and M1 genotypes with chronic liver diseases among Filipinos. Int J Mol Epidemiol Genet 3(2):153-159. www.ijmeg.org /ISSN1948-1756/IJMEG1204004.

Baclig MO, Predicala RZ, Mapua CA, Lozano-Kühne JP, Daroy MLG, Natividad FF, Javier FO (2012). Allelic and genotype frequencies of catechol-Omethyltransferase (Val158Met) and CYP2D6*10 (Pro34Ser) single nucleotide polymorphisms in the Philippines. Int J Mol Epidemiol Genet 3(2):115-121. www.ijmeg.org /ISSN1948-1756/IJMEG1203001.

Lozano-Kühne JP, Aguila MER, Manalang Jr GF, Chua RB, Gabud RS, Mendoza ER (2012). Shift work research in the Philippines: current state and future directions. Philippine Science Letters. 5(1), 17-29. 

Elsner L, Flügge PF, Lozano J, Muppala V, Eiz-Vesper B, Demiroglu SY, Malzahn D, Herrmann T, Brunner E, Bickeböller H, Multhoff G, Walter L, Dressel R (2010). The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells. Journal of Cellular and Molecular Medicine Vol 14, No 4, pp. 992-1002.

Malzahn D, Balavarca Y, Lozano JP, Bickeböller H (2009). Tests for candidate gene interaction for longitudinal quantitative traits measured in a large cohort. BMC Proceedings 2009, 3(Suppl 7):S80.

Elsner L, Muppala V, Gehrmann M, Lozano J, Malzahn D, Bickeböller H, Brunner E, Zientkowska M, Herrmann T, Walter L, Alves F, Multhoff G, Dressel R (2007). The heat shock protein HSP70 promotes mouse NK cell activity against tumors which express inducible NKG2D ligands. Journal of Immunology 179: 5523-5533.

Bickeböller H, Goddard KAB, Igo RP, Kraft P, Lozano JP, Prankratz N (2007). Issues in association mapping with high-density SNP data and diverse family structures. Genetic Epidemiology 31 (Supplement 1): S22-S33.

Guazon JLB, Lozano JP, Posas FEB, Calleja HB (2004). Chest radiograph aortic arch calcification is a surrogate marker of coronary artery disease. The Leading Edge in Cardiology 4  edited by Saavedra RD and Luque MPM. Heart Institute, St. Luke’s Medical Center, Quezon City, Philippines.

BOOKS and BOOK CHAPTERS

Lozano-Kühne J (2013). Cancer Resources. In: Encyclopedia of Systems Biology (Eds: Dubitzky W, Wolkenhauer   O, Yokota H, Cho K-H). New York:Springer. ISBN 978-1-4419-9863-7. 

Lozano-Kühne J (2013). Disease Databases. In: Encyclopedia of Systems Biology (Eds: Dubitzky W, Wolkenhauer O, Yokota H, Cho K-H). New York:Springer. ISBN 978-1-4419-9863-7.   

Lozano-Kühne J (2013). SNPedia. In: Encyclopedia of Systems Biology (Eds: Dubitzky W, Wolkenhauer O, Yokota H, Cho K-H). New York:Springer. ISBN 978-1-4419-9863-7.

Lozano JP (2010). Generalized Quantitative Transmission Disequilibrium Test for Analyzing Genetic Main Effects and Epistasis. Cuvillier Verlag Göttingen, Germany. 

Mendoza OM, Borja MP, Sevilla TL, Ancheta CA, Saniel OP, Sarol Jr JN, Lozano JP (2010). Foundations of Statistical Analysis for the Health Sciences. Department of Epidemiology and Biostatistics, College of Public Health, University of the Philippines Manila, Buencamino Press.   

OTHER PUBLICATIONS

Lozano-Kühne J (2012). Shift work in the Philippines in the cyber age. Star Science, Philippine Star. March 8, 2012. 

Lozano JP (2010). A generalized method for analyzing genetic main effects and epistasis among candidate genes using parent-offspring trios. Abstract Book of the 18th Annual Meeting of the Belgian Statistical Society. pp. 13, Spa, Belgium.

Lozano J (2010). Generalized Method in Candidate Gene Analysis for Nonnormally Distributed Quantitative Traits using Family Trios. Genetic Epidemiology. 34: 963-963. (Reported: Dec 2010, Conference paper). 

Elsner L, Fluegge PF, Lozano J, Muppala V, Demiroglu SY,   Malzahn D, Bickeboeller H, Multhoff G, Walter L, Dressel R (2008). The stress-inducible endogenous danger signals HSP70 and MICA synergistically activate the cytotoxic effector functions of human NK cells. Wiener Klinische Wochenschrift 120:22-22 (Reported Aug 2008, Conference Paper).

Lozano JP, Bickeboeller H (2008). Detecting Epistasis among Candidate Genes using Quantitative Traits and Family Trios. Genetic Epidemiology. 32: 705-705. (Reported Nov 2008, Conference paper). 

Lozano JP (2004). Biostatistics 201 Interactive Reference CD (Funded by the Diamond Jubilee Faculty Grant, University of the Philippines Manila, 2004)